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Article

Increased risk of gastrointestinal lymphoma in carriers of the 657del5 NBS1 gene mutation.

International journal of cancer - 15 Dec 2006

Steffen Jan, Maneva Galina, Popławska Lidia, Varon Raymonda, Mioduszewska Olga, Sperling Karl

Abstract excerpt

The NBS1 gene mutation, 657del5, frequent in the Slavic populations of Central Europe, is found in most patients with Nijmegen breakage syndrome (NBS), a recessive autosomal disorder with a very high incidence of non-Hodgkin lymphoma (NHL). We have previously described 2 heterozygous 657del5 mutation carriers among 42 adult NHL probands from Central Poland. Here we report 6 additional carriers of the 657del5...

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Source

Identifiers

PMID: 16998789
DOI: 10.1002/ijc.22280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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