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Article

Transcription factor MITF regulates cardiac growth and hypertrophy.

The Journal of clinical investigation - 1 Oct 2006

Tshori Sagi, Gilon Dan, Beeri Ronen, Nechushtan Hovav, Kaluzhny Dmitry, Pikarsky Eli, Razin Ehud

Abstract excerpt

High levels of microphthalmia transcription factor (MITF) expression have been described in several cell types, including melanocytes, mast cells, and osteoclasts. MITF plays a pivotal role in the regulation of specific genes in these cells. Although its mRNA has been found to be present in relatively high levels in the heart, its cardiac role has never been explored. Here we show that a specific heart isoform of...

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Source

Open in PubMed Open full text

Identifiers

PMID: 16998588
DOI: 10.1172/JCI27643
PMCID: PMC1570375

Genes

MITF
PAX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Transcription factor MITF regulates cardiac growth and hypertrophy.PMID 16998588Read ↗

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