Article
Circular single-stranded RNA replicon in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1990
Matsumoto Y, Fishel R, Wickner R B
Abstract excerpt
Circular RNA replicons have been reported in plants and, in one case, in animal cells. We describe such an element in yeast. In certain yeast strains, a 20S RNA species appears on transfer of cells to acetate medium. This phenotype shows cytoplasmic (non-Mendelian) inheritance and the 20S RNA is associated with 23-kDa protein subunits as a 32S particle. We demonstrate that yeast 20S RNA is an independent replicon...
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