Article
Modulation of intercellular adherens-type junctions and tyrosine phosphorylation of their components in RSV-transformed cultured chick lens cells.
Cell regulation - 1 Feb 1991
Volberg T, Geiger B, Dror R, Zick Y
Abstract excerpt
Transformation of cultured chick lens epithelial cells with a temperature-sensitive mutant of Rous sarcoma virus (tsRSV) leads to radical changes in cell shape and interactions. When cultured at the restrictive temperature (42 degrees C), the transformed cells largely retained epithelial morphology and intercellular adherens junctions (AJ), whereas on switch to the permissive temperature (37 degrees C) they...
Topics
- Animals
- Avian Sarcoma Viruses
- Cell Adhesion
- Cell Transformation, Viral
- Cells, Cultured
- Intercellular Junctions
- Lens, Crystalline
- Microscopy, Electron
- Mutation
- Phosphoprotein Phosphatases
- Phosphorylation
