Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The factor XIII Val34Leu polymorphism: is it protective against idiopathic venous thromboembolism?

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Oct 2006

Wells Philip S, Anderson Josdalyne L, Rodger Marc A, Carson Nancy, Grimwood Rebecca L, Doucette Steve P

Abstract excerpt

The substitution of leucine for valine at amino acid position 34 of the factor XIII gene is commonly referred to as FXIII Val34Leu polymorphism. The homozygous leucine/leucine genotype has been reported to confer protection against venous thromboembolism, but previous studies have not evaluated a population limited to those with idiopathic venous thromboembolism. The primary objective of the study was to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Factor XIII
Share to Leucine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Odds Ratio

Share to Risk Assessment

Share to Thromboembolism

Share to Valine

Share to Venous Thrombosis

Share to White People

Source

Identifiers

PMID: 16988547
DOI: 10.1097/01.mbc.0000245295.79891.86

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The factor XIII Val34Leu polymorphism: is it protective against idiopathic venous thromboembolism?PMID 16988547Read ↗

Factor XIII Val34Leu variant is protective against venous thromboembolism: a HuGE review and meta-analysis.Semantic proximity Read ↗

Fibrinogen Aalpha-Thr312Ala and factor XIII-A Val34Leu polymorphisms in idiopathic venous thromboembolism.Semantic proximity Read ↗

Factor XIII Val34Leu and the risk of venous thromboembolism in factor V Leiden carriers.Semantic proximity Read ↗

The FXIII Val34Leu polymorphism in venous and arterial thromboembolism.Semantic proximity Read ↗

Factor XIII Val34Leu is a genetic factor involved in the etiology of venous thrombosis.Semantic proximity Read ↗

Coagulation factor XII haploinsufficiency is protective against venous thromboembolism in a population-scale multidimensional analysisSemantic proximity Read ↗

Frequency of the TAFI -438 G/A and factor XIIIA Val34Leu polymorphisms in patients with objectively proven pulmonary embolism.Semantic proximity Read ↗

Factor XIII Val34Leu polymorphism in primary intracerebral haemorrhage.Semantic proximity Read ↗

Prevalence of the Factor XIII Val34Leu Polymorphism in Korean Patients with Deep Vein Thrombosis.Semantic proximity Read ↗

Factor XIII Val34Leu polymorphism, factor XIII antigen levels and activity and the risk of deep venous thrombosis.Semantic proximity Read ↗

Association of a common polymorphism in the factor XIII gene with venous thrombosis.Semantic proximity Read ↗

Association between the Val34Leu polymorphism in blood coagulation factor XIII-A and intracerebral hemorrhage: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.