Article
Polymorphism of the cytokine genes in hospitalized patients with Puumala hantavirus infection.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jul 2001
Mäkelä S, Hurme M, Ala-Houhala I, Mustonen J, Koivisto A M, Partanen J, Vapalahti O, Vaheri A, Pasternack A
Abstract excerpt
BACKGROUND: Nephropathia epidemica (NE) is a mild type of haemorrhagic fever with renal syndrome caused by Puumala (PUU) hantavirus. The clinical course of NE varies from asymptomatic to fatal. The aim of this study was to establish whether polymorphisms in the cytokine genes are associated with susceptibility to and outcome of NE. METHODS: The genotypes of the genes of tumour necrosis factor alpha (TNFalpha),...
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