Article
Allogeneic mesoangioblasts give rise to alpha-sarcoglycan expressing fibers when transplanted into dystrophic mice.
Experimental cell research - 15 Nov 2006
Guttinger Maria, Tafi Elisiana, Battaglia Manuela, Coletta Marcello, Cossu Giulio
Abstract excerpt
Cell therapy for muscular dystrophy involves transplantation of either genetically modified autologous cells or normal donor cells that will be rejected unless the host is adequately immune suppressed. The extent of the immune response appears to be mitigated in this case of stem cells, by immune-suppressive and tolerogenic molecules that they release. We previously reported significant morphological and...
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