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Article

A New Immunodeficient Mouse Model for Human Myoblast Transplantation

1 May 2001

Abstract excerpt

Design of efficient transplantation strategies for myoblast-based gene therapies in humans requires animal models in which xenografts are tolerated for long periods of time. In addition, such recipients should be able to withstand pretransplantation manipulations for enhancement of graft growth. Here we report that a newly developed immunodeficient mouse carrying two known mutations (the recombinase activating...

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PMID: 11339898
DOI: 10.1089/104303401750148784

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