Article
Dilated cardiomyopathy caused by LMNA mutations. Clinical and morphological studies.
Kardiologia polska - 1 Aug 2006
Bilińska Zofia T, Sylvius Nicolas, Grzybowski Jacek, Fidziańska Anna, Michalak Ewa, Walczak Ewa, Walski Michał, Bieganowska Katarzyna, Szymaniak Elzbieta, Kuśmierczyk-Droszcz Beata, Lubiszewska Barbara, Wagner Teresa, Tesson Frederique, Ruzyłło Witold
Abstract excerpt
BACKGROUND: Dilated cardiomyopathy (DCM) is familial in about 20-35% of patients. The most frequently encountered mutations associated with DCM are found in LMNA. AIM: To define the frequency of LMNA mutations in a series of consecutive DCM patients and to evaluate the phenotype of mutation carriers. METHODS: We screened the 12 exons of LMNA in a series of 61 Polish patients with DCM diagnosed angiographically,...
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