Article
Molecular cloning and characterization of acrA and acrE genes of Escherichia coli.
Journal of bacteriology - 1 Oct 1993
Ma D, Cook D N, Alberti M, Pon N G, Nikaido H, Hearst J E
Abstract excerpt
The DNA fragment containing the acrA locus of the Escherichia coli chromosome has been cloned by using a complementation test. The nucleotide sequence indicates the presence of two open reading frames (ORFs). Sequence analysis suggests that the first ORF encodes a 397-residue lipoprotein with a 24-amino-acid signal peptide at its N terminus. One inactive allele of acrA from strain N43 was shown to contain an IS2...
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