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Article

Allelic variation of Escherichia coli outer membrane protein A: Impact on cell surface properties, stress tolerance and allele distribution.

PloS one - 1 Jan 2022

Liao Chunyu, Santoscoy Miguel C, Craft Julia, Anderson Chiron, Soupir Michelle L, Jarboe Laura R

Abstract excerpt

Outer membrane protein A (OmpA) is one of the most abundant outer membrane proteins of Gram-negative bacteria and is known to have patterns of sequence variations at certain amino acids-allelic variation-in Escherichia coli. Here we subjected seven exemplar OmpA alleles expressed in a K-12 (MG1655) ΔompA background to further characterization. These alleles were observed to significantly impact cell surface...

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Identifiers

PMID: 36227900
DOI: 10.1371/journal.pone.0276046
PMCID: PMC9560509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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