Article
Recipient ctla-4 +49 G/G genotype is associated with reduced incidence of acute rejection after liver transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Dec 2003
de Reuver Philip, Pravica Vera, Hop Wim, Boor Patrick, Metselaar Herold J, Hutchinson Ian V, Tilanus Hugo W, Kwekkeboom Jaap
Abstract excerpt
The aim of this pilot study was to investigate whether acute rejection after liver transplantation is associated with known single-nucleotide polymorphisms (SNPs) in the CD86- and CTLA-4 genes of liver-transplant donors and recipients. Single nucleotide polymorphisms were determined in 135 liver transplant recipients and in 73 donors. Acute rejection was not associated with CD86 + 1057 G/A genotype distributions...
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