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Article

Template requirements for recognition and copying by Sindbis virus RNA-dependent RNA polymerase.

Virology - 5 Feb 2007

Thal Melissa A, Wasik Brian R, Posto Jessica, Hardy Richard W

Abstract excerpt

The Sindbis virus (SIN) nonstructural protein nsP4 possesses the RNA-dependent RNA polymerase activity required for the replication of the SIN genome and transcription of a subgenomic mRNA during infection. Isolation of this protein from other viral components of the RNA synthetic complex allowed the characterization of template requirements for nsP4-mediated genome replication. The major findings of this study...

Topics

3' Untranslated Regions
5' Untranslated Regions
Animals
Binding Sites
Cell Line
Cricetinae
Mutation
Nucleotides
RNA, Viral
Sindbis Virus
Templates, Genetic
Transcription, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Viral Nonstructural Proteins

Source

Identifiers

PMID: 16979682
DOI: 10.1016/j.virol.2006.08.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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