Article
Perlecan, the large low-density proteoglycan of basement membranes: structure and variant forms.
Kidney international - 1 Jan 1993
Noonan D M, Hassell J R
Abstract excerpt
The complete primary structure of perlecan, the large low-density proteoglycan of basement membranes, has been deduced by cDNA cloning for the mouse and more recently the human gene products. Mouse perlecan contains a 396 kDa core protein with five distinct domains: a heparan sulfate attachment domain, a LDL receptor-like domain, two different laminin-like domains and an N-CAM-like domain. These domains are...
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