Article
Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer.
Oncology reports - 1 Oct 2006
Staiger Wilko I, Coy Johannes F, Grobholz Rainer, Hofheinz Ralf-Dieter, Lukan Nadine, Post Stefan, Schwarzbach Matthias H, Willeke Frank
Abstract excerpt
The nonoxidative pentose phosphate pathway allows glucose conversion to ribose for DNA or RNA synthesis and glucose degradation to lactate controlled by transketolase enzyme reactions. It has been postulated, that this pathway is of the utmost importance in tumors for the proliferation process. W...
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