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The structure of the second cytosolic loop of the yeast mitochondrial ADP/ATP carrier AAC2 is dependent on the conformational state.

Mitochondrion - 1 Oct 2006

Iwahashi Akihiro, Kihira Yoshitaka, Majima Eiji, Terada Hiroshi, Yamazaki Naoshi, Kataoka Masatoshi, Shinohara Yasuo

Abstract excerpt

To detect structural changes in the second cytosolic loop of the mitochondrial ADP/ATP carrier of Saccharomyces cerevisiae AAC2, we prepared 20 single cysteine mutants by replacing each amino acid in the S213 to L232 region. All single cysteine mutants were fully functional, because they could restore growth on glycerol of a yeast strain lacking functional ADP/ATP carriers. First, these single-Cys mutants were...

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Identifiers

PMID: 16962388
DOI: 10.1016/j.mito.2006.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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