Article
The molecular basis for relative physiological functionality of the ADP/ATP carrier isoforms in Saccharomyces cerevisiae.
Genetics - 1 Jul 2008
Smith Christopher P, Thorsness Peter E
Abstract excerpt
AAC2 is one of three paralogs encoding mitochondrial ADP/ATP carriers in the yeast Saccharomyces cerevisiae, and because it is required for respiratory growth it has been the most extensively studied. To comparatively examine the relative functionality of Aac1, Aac2, and Aac3 in vivo, the gene encoding each isoform was expressed from the native AAC2 locus in aac1Delta aac3Delta yeast. Compared to Aac2, Aac1...
Topics
- Adenosine Triphosphate
- Amino Acid Sequence
- Codon
- DNA, Mitochondrial
- Gene Fusion
- Genes, Suppressor
- Mitochondrial ADP, ATP Translocases
- Molecular Sequence Data
- Mutation
- Phosphates
- Polymerase Chain Reaction
- Protein Isoforms
- Protein Transport
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Alignment