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Article

Functional characterization of PmHS1, a Pasteurella multocida heparosan synthase.

The Journal of biological chemistry - 3 Nov 2006

Kane Tasha A, White Carissa L, DeAngelis Paul L

Abstract excerpt

Heparosan synthase 1 (PmHS1) from Pasteurella multocida Type D is a dual action glycosyltransferase enzyme that transfers monosaccharide units from uridine diphospho (UDP) sugar precursors to form the polysaccharide heparosan (N-acetylheparosan), which is composed of alternating (-alpha4-GlcNAc-beta1,4-GlcUA-1-) repeats. We have used molecular genetic means to remove regions nonessential for catalytic activity...

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PMID: 16959770
DOI: 10.1074/jbc.M606897200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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