Article
Role of protein phosphatases 2C on tolerance to lithium toxicity in the yeast Saccharomyces cerevisiae.
Molecular microbiology - 1 Oct 2006
Ruiz Amparo, González Asier, García-Salcedo Raúl, Ramos José, Ariño Joaquín
Abstract excerpt
Protein phosphatases 2C are a family of conserved enzymes involved in many aspects of the cell biology. We reported that, in the yeast Saccharomyces cerevisiae, overexpression of the Ptc3p isoform resulted in increased lithium tolerance in the hypersensitive hal3 background. We have found that the tolerance induced by PTC3 overexpression is also observed in wild-type cells and that this is most probably the...
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