Article
Low replication and variability of HBV pre-core in concomitant infection with hepatitis B and hepatitis C viruses.
Archives of virology - 1 Feb 2007
De Mitri M S, Morsica G, Cassini R, Bagaglio S, Andreone P, Bianchi G, Loggi E, Bernardi M
Abstract excerpt
In an attempt to define the virological profile of HBV in HCV co-infection, we analysed the viral load, the infecting genotype, and the mutational pattern of the HBV pre-core region (pre-C), which is involved in viral encapsidation and DNA replication. Eighty-six patients were studied: 32 with serological HBV/HCV-1b co-infection (group BC), 32 infected by HBV alone (group B), and 22 by HCV-1b alone (group C)....
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