Article
Terminal deoxynucleotidyl transferase and CD7 expression in acute myeloid leukemias are not associated with a high frequency of immunoglobulin and/or T cell receptor gene rearrangement.
Leukemia - 1 Apr 1990
Willière G, Stockinger H, Köller U, Majdic O, Schnabl E, Lutz D, Bettelheim P, Knapp W
Abstract excerpt
Within normal hemopoiesis, the intranuclear DNA polymerase TdT seems to be exclusively expressed by T and B lymphoid precursor cells. Double staining experiments showed that TdT can also be expressed in blast cells of certain acute myeloid leukemias. Recent reports described a very strong associa...
Topics
- Antigens, CD7
- Antigens, Differentiation, T-Lymphocyte
- DNA Nucleotidylexotransferase
- Gene Rearrangement, T-Lymphocyte
- Humans
- Immunoglobulin Heavy Chains
- Leukemia, Monocytic, Acute
- Leukemia, Myeloid, Acute
- Leukemia, Myelomonocytic, Acute
- Leukemia, Promyelocytic, Acute
- Phenotype
- Receptors, Antigen, T-Cell