Article
The immunologic detection of minimal residual disease in acute leukemia.
Blood - 1 Jul 1990
Campana D, Coustan-Smith E, Janossy G
Abstract excerpt
Certain combinations of differentiation antigens are expressed on leukemia blasts and are absent or extremely rare among normal progenitors in the fetal liver and fetal and regenerating bone marrow. These combinations include cCD3/TdT, a thymic feature retained on thymic-acute lymphoblastic leukemia (T-ALL) blasts outside the thymus, and the coexpression of TdT and myeloid markers (CD13, CD33) on a proportion of...
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