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Terminal transferase positive acute myeloid leukemia: immunophenotypic characterization and response to induction therapy.

Hematological oncology - 1 Jan 2000

Lo Coco F, Lopez M, Pasqualetti D, Montefusco E, Cafolla A, Monarca B, Sgadari C, De Rossi G

Abstract excerpt

A quantitative evaluation of terminal deoxynucleotidyl transferase (TdT) was performed using a highly sensitive enzyme immunoassay (EIA) in 72 previously untreated patients with acute myeloid leukemia (AML). Biological analysis of the leukemic cells included in all cases cytochemistry, search for Ph' chromosome and immunophenotyping with both anti-lymphoid and anti-myeloid monoclonal antibodies (MoAbs). Thirteen...

Topics

Adolescent
Adult
Aged
DNA Nucleotidylexotransferase
Female
Fluorescent Antibody Technique
Humans
Immunoenzyme Techniques
Leukemia, Myeloid, Acute
Male
Middle Aged

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PMID: 2646199
DOI: 10.1002/hon.2900070208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2646199-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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