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Article

Oriented scanning is the leading mechanism underlying 5' splice site selection in mammals.

PLoS genetics - 1 Sept 2006

Borensztajn Keren, Sobrier Marie-Laure, Duquesnoy Philippe, Fischer Anne-Marie, Tapon-Bretaudière Jacqueline, Amselem Serge

Abstract excerpt

Splice site selection is a key element of pre-mRNA splicing. Although it is known to involve specific recognition of short consensus sequences by the splicing machinery, the mechanisms by which 5' splice sites are accurately identified remain controversial and incompletely resolved. The human F7 gene contains in its seventh intron (IVS7) a 37-bp VNTR minisatellite whose first element spans the exon7-IVS7...

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Identifiers

PMID: 16948532
DOI: 10.1371/journal.pgen.0020138
PMCID: PMC1557585

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Source receipt: pubmed, retrieved 7 Sept 2026.

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