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Article

Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice.

Nucleic acids research - 1 Jan 2006

De Souza Angus T, Dai Xudong, Spencer Andrew G, Reppen Tom, Menzie Ann, Roesch Paula L, He Yudong, Caguyong Michelle J, Bloomer Sherri, Herweijer Hans, Wolff Jon A, Hagstrom James E, Lewis David L, Linsley Peter S, Ulrich Roger G

Abstract excerpt

RNA interference (RNAi) has great potential as a tool for studying gene function in mammals. However, the specificity and magnitude of the in vivo response to RNAi remains to be fully characterized. A molecular and phenotypic comparison of a genetic knockout mouse and the corresponding knockdown...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16945951
DOI: 10.1093/nar/gkl609
PMCID: PMC1636368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16945951-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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