Article
DJ1 analysis in a large cohort of Italian early onset Parkinson Disease patients.
Neuroscience letters - 17 Dec 2013
Sironi Francesca, Primignani Paola, Ricca Sara, Tunesi Sara, Zini Michela, Tesei Silvana, Cilia Roberto, Pezzoli Gianni, Seia Manuela, Goldwurm Stefano
Abstract excerpt
We analyzed the DJ1 gene in a large consecutive series (N=163) of Italian unrelated Early Onset Parkinson Disease (EOPD: onset ≤40 years of age) patients and 100 healthy controls (mean age 64 ± 7 years). No homozygous or compound heterozygous mutations with an obvious pathogenic effect were found. Several variants were identified, some of which were novels. All variants had similar frequency in patients and in...
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