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Article

Hereditary Parkinson’s disease as a new clinical manifestation of the damaged POLG gene

Orvosi hetilap - 1 May 2020

Illés Anett, Balicza Péter, Gál Anikó, Pentelényi Klára, Csabán Dóra, Gézsi András, Molnár Viktor, Molnár Mária Judit

Abstract excerpt

The protein product of the nuclear-encoded POLG gene plays a key role in the maintenance of mitochondrial DNA replication, and its failure causes multi-system diseases with varying severity. The clinical spectrum is extremely wide, and the most common symptoms include ptosis, myoclonus, epilepsy, myopathy, sensory ataxia, parkinsonism, cognitive decline and infertility. Now, it is known that mitochondrial...

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Identifiers

PMID: 32364361
DOI: 10.1556/650.2020.31724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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