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Article

Duodenal carcinoma in MUTYH-associated polyposis

30 Aug 2006

Abstract excerpt

Bi-allelic germline mutations in the MUTYH gene give rise to multiple adenomas and an increased incidence of colorectal cancer. In addition, duodenal adenomas and other extra-colonic manifestations have been described in MUTYH-associated polyposis (MAP) patients. We describe two patients with bi-allelic MUTYH gene mutations with duodenal carcinoma. The tumour in Patient A was detected during evaluation of...

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Identifiers

PMID: 16943222
DOI: 10.1136/jcp.2005.031757

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