Article
Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton.
The Journal of cell biology - 23 Mar 2009
Lin Fang, Chen Songhai, Sepich Diane S, Panizzi Jennifer Ray, Clendenon Sherry G, Marrs James A, Hamm Heidi E, Solnica-Krezel Lilianna
Abstract excerpt
Epiboly spreads and thins the blastoderm over the yolk cell during zebrafish gastrulation, and involves coordinated movements of several cell layers. Although recent studies have begun to elucidate the processes that underlie these epibolic movements, the cellular and molecular mechanisms involve...
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