Article
Experience in preimplantation genetic diagnosis for exclusion of homozygous alpha degrees thalassemia.
Prenatal diagnosis - 1 Nov 2006
Chan Vivian, Ng Ernest H Y, Yam Irene, Yeung William S B, Ho P C, Chan T K
Abstract excerpt
OBJECTIVE: To report our experience in preimplantation genetic diagnosis (PGD) for the exclusion of homozygous alpha degrees thalassemia. PATIENTS AND METHODS: PGD was performed on nine couples with alpha degrees thalassemia genotype undergoing assisted reproduction. Oocytes were aspirated after ovarian stimulation and fertilized by intracytoplasmic sperm injection. One or two blastomeres were biopsied from the...
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