Article
Fetal hemoglobin in normal adults and beta-thalassemia heterozygotes.
Human genetics - 1 Jun 1990
Kutlar A, Kutlar F, Gu L G, Mayson S M, Huisman T H
Abstract excerpt
A recently developed high performance liquid chromatographic (HPLC) procedure using a weak cation exchanger (PolyCAT) in columns of different sizes was used to quantify fetal hemoglobin (HbF) in blood of normal adults and beta-thalassemia (beta-thal) heterozygotes with ten different types of mutations. Preparative PolyCAT-HPLC greatly facilitated the characterization of isolated HbF, i.e., the determination of...
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