Hb Sinai-Baltimore or alpha 2 beta (2)18(A15)Val->Gly, a silent, mildly unstable beta chain variant detected by isoelectrofocusing and high performance liquid chromatography.

doi:10.3109/03630269309043490

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Article

Hb Sinai-Baltimore or alpha 2 beta (2)18(A15)Val->Gly, a silent, mildly unstable beta chain variant detected by isoelectrofocusing and high performance liquid chromatography.

Hemoglobin - 1 Dec 1993

Pobedimskaya D D, Molchanova T P, Amernick R, Druskin M S, Webber B B, Wilson J B, Huisman T H

Abstract excerpt

Isoelectrofocusing and high performance liquid chromatographic methods were used to study an abnormal hemoglobin present in a Black male infant and his mother. The variant, named Hb Sinai-Baltimore, focused slightly behind Hb A and separated incompletely from Hb A by cation exchange high performa...

Topics

Chromatography, High Pressure Liquid
Female
Hemoglobins, Abnormal
Heterozygote
Humans
Infant
Isoelectric Focusing
Male
Mutation

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