Article
Two alpha-chain hemoglobin variants, Hb Broussais and Hb Cemenelum, characterized by cation-exchange HPLC, isoelectric focusing, and peptide sequencing.
Clinical chemistry - 1 Apr 1995
Turpeinen U, Sipilä I, Anttila P, Karjalainen U, Kuronen B, Kalkkinen N, Ahola T, Stenman U H
Abstract excerpt
We here report the characteristics of two rare alpha-chain hemoglobin (Hb) variants. The variants were found during quantification of HbA1c by cation-exchange HPLC with the Diamat glycohemoglobin analyzer. They were further characterized by isoelectric focusing and PolyCAT A cation-exchange chrom...
Topics
- Adolescent
- Amino Acid Sequence
- Cations
- Child
- Chromatography, High Pressure Liquid
- Female
- Globins
- Glycated Hemoglobin
- Hemoglobins, Abnormal
- Humans
- Isoelectric Focusing
- Isoelectric Point
- Male
- Molecular Sequence Data
- Mutation
- Reference Values
- Sequence Analysis