Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

How genetic analysis tests theories of animal aging.

Nature genetics - 1 Sept 2006

Hekimi Siegfried

Abstract excerpt

Each animal species displays a specific life span, rate of aging and pattern of development of age-dependent diseases. The genetic bases of these related features are being studied experimentally in invertebrate and vertebrate model systems as well as in humans through medical records. Three types of mutants are being analyzed: (i) short-lived mutants that are prone to age-dependent diseases and might be models...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Cellular Senescence
Share to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Forecasting

Share to Longevity

Share to Models, Genetic

Share to Models, Theoretical

Source

Identifiers

PMID: 16941009
DOI: 10.1038/ng1881

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

How genetic analysis tests theories of animal aging.PMID 16941009Read ↗

Mutant models of prolonged life span.Semantic proximity Read ↗

Mammalian models of extended healthy lifespan.Semantic proximity Read ↗

Longevity: Lesson from Model OrganismsSemantic proximity Read ↗

Kleemeier award lecture: are there genes for aging?Semantic proximity Read ↗

Animal Models of Aging Research: Implications for Human Aging and Age-Related DiseasesSemantic proximity Read ↗

Generation and Identification of Mutations Resulting in Chronic and Age-Related Phenotypes in Mice.Semantic proximity Read ↗

Do longevity mutants always show trade-offs?Semantic proximity Read ↗

The plasticity of aging: insights from long-lived mutants.Semantic proximity Read ↗

Subfield history: use of model organisms in the search for human aging genes.Semantic proximity Read ↗

Genetic pathways that regulate ageing in model organisms.Semantic proximity Read ↗

Invertebrate gerontology: the age mutations of Caenorhabditis elegans.Semantic proximity Read ↗

Mouse Models to Disentangle the Hallmarks of Human AgingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.