Article
A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan.
Annals of clinical microbiology and antimicrobials - 26 Aug 2006
Adam Ishag, Magzoub Mamoun, Osman Maha E, Khalil Insaf F, Alifrangis Michael, Elmardi Khalid A
Abstract excerpt
BACKGROUND: Artemisinin-based combination therapy is increasingly being adopted as first-line antimalarial therapy. The choice of appropriate therapy depends on efficacy, cost, side effects, and simplicity of administration. METHODS: the efficacy of fixed co-formulated (f) artesunate-sulfamethoxypyrazine-pyrimethamine (AS+SMP f) administered at time intervals of 12 hours for a 24-hour therapy was compared with...
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