Article
Therapeutic efficacy of fixed dose artesunate-mefloquine for the treatment of acute, uncomplicated Plasmodium falciparum malaria in Kampong Speu, Cambodia.
Malaria journal - 23 Sept 2013
Leang Rithea, Ros Sakun, Duong Socheat, Navaratnam Visweswaran, Lim Pharath, Ariey Frédéric, Kiechel Jean-René, Ménard Didier, Taylor Walter R J
Abstract excerpt
BACKGROUND: Cambodia stopped using co-blistered, non-fixed, artesunate-mefloquine (ASMQ) in 2008 when treatment failure rates approximated 20%. Fixed dose combination (FDC) ASMQ is efficacious against acute uncomplicated, drug resistant Plasmodium falciparum malaria in Southeast Asia but has not been tested in Cambodia. METHODS: A 42-day WHO therapeutic efficacy study (TES) was conducted in 2010 in Oral, Kampong...
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