Article
Genetic manipulation of a primary metabolic pathway for L-ornithine production in Escherichia coli.
Biotechnology letters - 1 Nov 2006
Lee Young-Joon, Cho Jae-Yong
Abstract excerpt
Metabolic engineering has been used to improve L-ornithine biosynthesis in Escherichia coli W3110. L-Ornithine production increased from 0.3 to 3.2 mg/g (dry cell weight) when the primary L-ornithine biosynthetic pathway was optimized by disrupting the pathway transcription repressor, thereby inc...
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