Article
Response to long-term lamivudine treatment in patients infected with hepatitis B virus genotypes A, B, and C.
Journal of medical virology - 1 Oct 2006
Kobayashi Mariko, Suzuki Fumitaka, Akuta Norio, Suzuki Yoshiyuki, Arase Yasuji, Ikeda Kenji, Hosaka Tetsuya, Sezaki Hitomi, Kobayashi Masahiro, Iwasaki Satomi, Sato Junko, Watahiki Sachiyo, Miyakawa Yuzo, Kumada Hiromitsu
Abstract excerpt
Response to lamivudine treatment longer than 1 year was compared in 15 patients persistently infected with hepatitis B virus (HBV) genotype A, 38 with genotype B, and 449 with genotype C. Patients with genotype A were younger (median age 37 [range 24-49] vs. 47 [24-67] or 44 [18-73], P = 0.015), possessed hepatitis B e antigen (HBeAg) more frequently (73% vs. 21% or 56%, P < 0.001) and HBV DNA in higher levels...
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