Unveiling the pathogenic mechanisms of Clostridium perfringens toxins and virulence factors

Abstract excerpt

Clostridium perfringens causes multiple diseases in humans and animals.Its pathogenic effect is supported by a broad and heterogeneous arsenal of toxins and other virulence factors associated with a specific host tropism.Molecular approaches have indicated that most C. perfringens toxins produce membrane pores, leading to osmotic cell disruption and apoptosis.However, identifying mechanisms involved in cell...

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