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Article

Thioredoxin 1 promotes intracellular replication and virulence of Salmonella enterica serovar Typhimurium.

Infection and immunity - 1 Sept 2006

Bjur Eva, Eriksson-Ygberg Sofia, Aslund Fredrik, Rhen Mikael

Abstract excerpt

The effect of the cytoplasmic reductase and protein chaperone thioredoxin 1 on the virulence of Salmonella enterica serovar Typhimurium was evaluated by deleting the trxA, trxB, or trxC gene of the cellular thioredoxin system, the grxA or gshA gene of the glutathione/glutaredoxin system, or the dsbC gene coding for a thioredoxin-dependent periplasmic disulfide bond isomerase. Mutants were tested for tolerance to...

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Identifiers

PMID: 16926406
DOI: 10.1128/IAI.00449-06
PMCID: PMC1594827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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