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Alpha-Toxin of<i>Clostridium perfringens</i>Is Not an Essential Virulence Factor in Necrotic Enteritis in Chickens

20 Oct 2006

Abstract excerpt

The Clostridium perfringens alpha-toxin has previously been implicated as the major virulence factor in necrotic enteritis in chickens, although definitive proof has not been reported. In this study an alpha-toxin mutant was constructed in a virulent chicken isolate and shown to retain full virulence in a chicken disease model. These results demonstrated that alpha-toxin is not an essential virulence factor in...

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Identifiers

PMID: 16923791
DOI: 10.1128/iai.00806-06

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