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Protein Truncating Variants of colA in Clostridium perfringens Type G Strains

29 Apr 2021

Abstract excerpt

Extracellular matrix (ECM) degrading enzymes produced by Clostridium perfringens may play an important role during the initial phases of avian necrotic enteritis by facilitating toxin entry in the intestinal mucosa and destruction of the tissue. C. perfringens is known to produce several ECM-degrading proteases, such as kappa toxin, an extracellular collagenase that is encoded by the colA gene. In this study, the...

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PMID: 33996628
DOI: 10.3389/fcimb.2021.645248

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