Article
The ESAT-6/CFP-10 secretion system of Mycobacterium marinum modulates phagosome maturation.
Cellular microbiology - 1 Sept 2006
Tan Tracy, Lee Warren L, Alexander David C, Grinstein Sergio, Liu Jun
Abstract excerpt
Virulence of Mycobacterium tuberculosis and related pathogenic mycobacteria requires the secretion of early secretory antigenic 6 kDa (ESAT-6) and culture filtrate protein 10 (CFP-10), two small proteins that lack traditional signal sequences and are exported through an alternative secretion pathway encoded primarily by the RD1 genetic locus. Mutations affecting the synthesis or secretion of ESAT-6 or CFP-10...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
