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Article

Targeting c-Myc, Ras and IGF Cascade to Treat Cancer and Vascular Disorders

1 Aug 2006

Abstract excerpt

Cancer and vascular diseases remain the predominant causes of morbidity and mortality in industrialized countries worldwide. The course of atherosclerosis with initiation, progression, and complication parallels the three stages of carcinogenesis with induction, growth, and invasion of tissue and neoangiogenesis. Within this framework, the oncogene c-Myc and growth factors pathways are acquiring increasing...

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PMID: 16921263
DOI: 10.4161/cc.5.15.3138

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