Article
GABA(A) receptor mediated transmission in the thalamic reticular nucleus of rats with genetic absence epilepsy shows regional differences: functional implications.
Brain research - 21 Sept 2006
Aker Rezzan Gülhan, Ozyurt Hazan B, Yananli Hasan R, Cakmak Yusuf Ozgür, Ozkaynakçi Aydan E, Sehirli Umit, Saka Erdinç, Cavdar Safiye, Onat Filiz Yilmaz
Abstract excerpt
The aim of the present study was to investigate the effect of local injections of the GABA(A) receptor antagonist, bicuculline, into the rostral and caudal parts of the thalamic reticular nucleus (TRN), on the generation of spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg (GAERS). Spike-and-wave discharges are important in the pathophysiology of absence epilepsy and generated by the...
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