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Article

Increased inhibitory synaptic activity in the hippocampus (CA1) of genetic absence epilepsy rats: Relevance of kindling resistance.

Epilepsy research - 1 Oct 2016

Çarçak Nihan, Dileköz Ergin, Gülhan Rezzan, Onur Rüştü, Onat Filiz Yılmaz, Sara Yıldırım

Abstract excerpt

PURPOSE: Genetic absence epilepsy rats from Strasbourg (GAERS), a well-validated genetic rat model for typical absence epilepsy, are known to manifest a resistance to secondary generalization of abnormal focal electrical activity evoked by kindling. The mechanism of this resistance is still unclear. In order to understand the possible mechanism of kindling resistance, we investigated for the first time, the...

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CA1 Region, Hippocampal
Electric Stimulation
Epilepsy, Absence
Neural Inhibition
Neuronal Plasticity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Synaptic Transmission

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PMID: 27434859
DOI: 10.1016/j.eplepsyres.2016.06.013

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