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Attenuation of very virulent infectious bursal disease virus and comparison of full sequences of virulent and attenuated strains

1 Apr 2008

Abstract excerpt

A very virulent strain of infectious bursal disease virus (IBDVks) was isolated from the bursae of Fabricius of IBDV-affected broiler chickens. Following 43 serial passages in specific pathogen-free embryonated eggs, an attenuated strain was established (IBDVmb). Dosages of IBDVmb in the range 10(2) to 10(4) embryo infective dose of 50% were found to be safe and protective for commercial chicks. Chickens...

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PMID: 18393093
DOI: 10.1080/03079450801910206

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