Article
Sequence variations of Epstein-Barr virus LMP1 gene in nasal NK/T-cell lymphoma.
Virus genes - 1 Jan 2007
Nagamine Masayoshi, Takahara Miki, Kishibe Kan, Nagato Toshihiro, Ishii Hideyuki, Bandoh Nobuyuki, Ogino Takeshi, Harabuchi Yasuaki
Abstract excerpt
Nasal natural killer (NK)/T-cell lymphoma is a peculiar lymphoma with an unique immunophenotype. Etiologically, the authors previously first demonstrated the presence of Epstein-Barr virus (EBV) genomes and their products in this lymphoma (Lancet 1990; 335). It is suggested that some of sequence variations such as a 30-bp deletion and multiple base substitutions and as amino acid changes at HLA-A2 restricted CTL...
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