Article
Genetic heterogeneity of granulocytes for the JAK2 V617F mutation in essential thrombocythaemia: implications for mutation detection in peripheral blood.
Pathology - 1 Aug 2006
Stevenson William S, Hoyt Rosemary, Bell Anthony, Guipponi Michel, Juneja Surender, Grigg Andrew P, Curtis David J, Scott Hamish S, Szer Jeff, Alexander Warren S, Tuckfield Annabel, Roberts Andrew W
Abstract excerpt
AIMS: The molecular pathogenesis of essential thrombocythaemia (ET) is heterogeneous. We aimed to determine the relative sensitivity of four separate molecular assays used to detect the presence of the JAK2 V617F mutation in peripheral blood from patients with essential thrombocythaemia and relat...
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