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Article

Acute myeloid leukemia subgroups identified by pathway-restricted gene expression signatures.

Acta haematologica - 1 Jan 2006

Serrano Elena, Lasa Adriana, Perea Granada, Carnicer Maria J, Brunet Salut, Aventín Anna, Sierra Jorge, Nomdedéu Josep F

Abstract excerpt

Acute myeloid leukemia (AML) is a heterogeneous group of disorders characterized by abnormal proliferation of myeloid precursors and a maturation block. Underlying genetic lesions determine an altered expression program (transcriptosome) that can be studied in depth by massive technologies. Alternatively, we selected a pathway profiling strategy based on the current knowledge in order to stratify de novo AML...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16914901
DOI: 10.1159/000093636

Genes

FLT3
ATRX
DNMT1
FOS
HDAC2
NDST1
RAD50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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